Molecular & Cellular Mechanisms of Dementia

Understanding the molecular and cellular mechanisms underlying dementia is essential for the development of new therapeutic strategies. This topic examines the biological processes contributing to neurodegeneration, including protein misfolding, synaptic dysfunction, mitochondrial impairment, oxidative stress, and neuroinflammatory pathways. Attendees will learn about experimental models, including cellular and animal systems, which provide insights into disease mechanisms and enable preclinical testing of potential treatments. Recent advances in genomics, proteomics, and transcriptomics will be explored, demonstrating how high-throughput technologies are uncovering new molecular targets and pathways relevant to various forms of dementia. Emphasis will also be placed on translational research, illustrating how discoveries in the laboratory are being applied to clinical practice to improve diagnosis, treatment, and patient outcomes. Discussions will highlight the importance of interdisciplinary collaboration between basic scientists, clinical researchers, and healthcare professionals in accelerating therapeutic development. Participants will gain a comprehensive understanding of how molecular insights can inform drug discovery, personalized medicine, and innovative care approaches. By connecting foundational research with clinical application, attendees will be empowered to contribute to the next generation of dementia therapies and enhance the overall understanding of neurodegenerative diseases.

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